产品名称
GNAO Rabbit Polyclonal Antibody
蛋白名称
Guanine nucleotide-binding protein G(o) subunit alpha
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
P09471
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P09471/entry
Mouse Swissprot No.
P18872
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P18872
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941P59215
免疫原
Synthesized peptide derived from part region of human protein
特异性
GNAO Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene represents the alpha subunit of the Go heterotrimeric G-protein signal-transducing complex. Defects in this gene are a cause of early-onset epileptic encephalopathy. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2015],
组织表达
Brain,Endometrium,Myometrium,
细胞定位
Cell membrane . Membrane ; Lipid-anchor .
信号通路
Long-term depression;Melanogenesis;
功能
function:Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(o) protein function is not clear.,similarity:Belongs to the G-alpha family. G(i/o/t/z) subfamily.,subunit:G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
