产品名称
GNA12 Rabbit Polyclonal Antibody
蛋白名称
Guanine nucleotide-binding protein subunit alpha-12 (G alpha-12) (G-protein subunit alpha-12)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q03113
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q03113/entry
Mouse Swissprot No.
P27600
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P27600
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941Q63210
免疫原
Synthesized peptide derived from part region of human protein
特异性
GNA12 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
function:Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.,similarity:Belongs to the G-alpha family. G(12) subfamily.,subunit:G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site. Interacts with UBXD5.,
组织表达
Brain,Pancreas,Placenta,Uterus,
细胞定位
Cell membrane ; Lipid-anchor . Lateral cell membrane ; Lipid-anchor . Cytoplasm . CDH1 enhances cell membrane localization. .
信号通路
MAPK_ERK_Growth;MAPK_G_Protein;Vascular smooth muscle contraction;Long-term depression;Regulates Actin and Cytoskeleton;
功能
function:Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.,similarity:Belongs to the G-alpha family. G(12) subfamily.,subunit:G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site. Interacts with UBXD5.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
