产品名称
RIT2 Rabbit Polyclonal Antibody
蛋白名称
GTP-binding protein Rit2 (Ras-like protein expressed in neurons) (Ras-like without CAAX protein 2)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q99578
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q99578/entry
Mouse Swissprot No.
P70425
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P70425
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941Q5BJQ5
免疫原
Synthesized peptide derived from part region of human protein
特异性
RIT2 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
RIN belongs to the RAS (HRAS; MIM 190020) superfamily of small GTPases (Shao et al., 1999 [PubMed 10545207]).[supplied by OMIM, Mar 2008],
细胞定位
Nucleus . Cell membrane . Colocalizes with PLXNB3 at the plasma membrane (PubMed:16122393). .
功能
function:Binds and exchanges GTP and GDP.,miscellaneous:Shows rapid uncatalyzed guanine nucleotide dissociation rates, which are much faster than those of most Ras subfamily members.,similarity:Belongs to the small GTPase superfamily. Ras family.,subunit:Interacts with MLLT4, the C-terminal domain of RALGDS and RLF, but not with RIN1 and PIK3CA. RLF binds exclusively to the active GTP-bound form (By similarity). Binds calmodulin.,tissue specificity:Neuron-specific.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
