产品名称
GNAO Rabbit Polyclonal Antibody
蛋白名称
Guanine nucleotide-binding protein G(o) subunit alpha
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
P09471
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P09471/entry
Mouse Swissprot No.
P18872
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P18872
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941P59215
免疫原
Synthesized peptide derived from part region of human protein
特异性
GNAO Polyclonal Antibody detects endogenous levels of protein.
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene represents the alpha subunit of the Go heterotrimeric G-protein signal-transducing complex. Defects in this gene are a cause of early-onset epileptic encephalopathy. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2015],
组织表达
Brain,Endometrium,Myometrium,
细胞定位
Cell membrane . Membrane ; Lipid-anchor .
信号通路
Long-term depression;Melanogenesis;
功能
function:Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(o) protein function is not clear.,similarity:Belongs to the G-alpha family. G(i/o/t/z) subfamily.,subunit:G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
