产品名称
DIRA3 Rabbit Polyclonal Antibody
基因名称
DIRAS3 ARHI NOEY2 RHOI
蛋白名称
GTP-binding protein Di-Ras3 (Distinct subgroup of the Ras family member 3) (Rho-related GTP-binding protein RhoI)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
O95661
Human Swissprot Link
https://www.uniprot.org/uniprotkb/O95661/entry
免疫原
Synthesized peptide derived from part region of human protein
特异性
DIRA3 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the ras superfamily. This gene is imprinted gene with monoallelic expression of the paternal allele which is associated with growth suppression. The encoded protein acts as a tumor suppressor whose function is abrogated in many ovarian and breast cancers. This protein may also play a role autophagy in certain cancer cells by regulating the autophagosome initiation complex. [provided by RefSeq, Nov 2015],
组织表达
Expressed in normal ovarian and breast epithelial cells but not in ovarian and breast cancers.
细胞定位
Cell membrane ; Lipid-anchor ; Cytoplasmic side .
功能
online information:NOEY2 entry,similarity:Belongs to the small GTPase superfamily. Di-Ras family.,tissue specificity:Expressed in normal ovarian and breast epithelial cells but not in ovarian and breast cancers.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
