产品名称
FIGL1 Rabbit Polyclonal Antibody
蛋白名称
Fidgetin-like protein 1 (EC 3.6.4.-)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q6PIW4
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q6PIW4/entry
Mouse Swissprot No.
Q8BPY9
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8BPY9
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941Q6GX84
免疫原
Synthesized peptide derived from part region of human protein
特异性
FIGL1 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
catalytic activity:ATP + H(2)O = ADP + phosphate.,cofactor:Magnesium.,function:May regulate osteoblast proliferation and differentiation.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the AAA ATPase family.,subunit:Hexamer.,
组织表达
Ovary,Pancreas,Skin,Testis,
细胞定位
Nucleus . Cytoplasm . Cytoplasm, perinuclear region . Together with RAD51 and a subset of H2A histone proteins, redistributed in discrete nuclear DNA damage-induced foci after ionizing radiation (IR) treatment (PubMed:23754376).
功能
catalytic activity:ATP + H(2)O = ADP + phosphate.,cofactor:Magnesium.,function:May regulate osteoblast proliferation and differentiation.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the AAA ATPase family.,subunit:Hexamer.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.