产品名称
USP34 Rabbit Polyclonal Antibody
别名
Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.4.19.12) (Deubiquitinating enzyme 34) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34)
基因名称
USP34 KIAA0570 KIAA0729
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=9736
Human Swissprot No.
Q70CQ2
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q70CQ2/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/17847
Mouse Swissprot No.
Q6ZQ93
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q6ZQ93
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/0
特异性
This antibody detects endogenous levels of USP34 at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Expressed in brain at low level.
细胞定位
SAGA complex,cytosol,
功能
catalytic activity:Ubiquitin C-terminal thioester + H(2)O = ubiquitin + a thiol.,function:Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquinated proteins.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the peptidase C19 family.,tissue specificity:Expressed in brain at low level.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.