BD-PT8016

EPH B1/3/4 Rabbit Polyclonal Antibody

Ephrin type-B receptor 1 (EC 2.7.10.1) (ELK) (EPH tyrosine kinase 2) (EPH-like kinase 6) (EK6) (hEK6) (Neuronally-expressed EPH-related tyrosine kinase) (NET) (Tyrosine-protein kinase receptor EPH-2)

常规抗体

EPHB1 ELK EPHT2 HEK6 NET

EPH B1/3/4

WB

Human,Mouse,Rat

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

2047

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=2047

P54762

https://www.uniprot.org/uniprotkb/P54762/entry

270190

https://www.uniprot.org/uniprot/270190

Q8CBF3

https://www.uniprot.org/uniprotkb/Q8CBF3

24338

https://www.uniprot.org/uniprot/24338

P09759

https://www.uniprot.org/uniprotkb/P09759

This antibody detects endogenous levels of EPH B1/3/4 at Human, Mouse,Rat

WB 1:500-2000

108kD

-15°C to -25°C/1 year(Do not lower than -25°C)

Preferentially expressed in brain.

Cell membrane ; Single-pass type I membrane protein . Early endosome membrane . Cell projection, dendrite .

catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,function:Receptor for members of the ephrin-B family. Binds to ephrin-B1, -B2 and -B3. May be involved in cell-cell interactions in the nervous system.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 SAM (sterile alpha motif) domain.,similarity:Contains 2 fibronectin type-III domains.,subunit:The ligand-activated form interacts with GRB2, GRB10 and NCK through their respective SH2 domains. The GRB10 SH2 domain binds EPHB1 through Tyr-928, while GRB2 binds residues within the catalytic domain. Interacts with EPHB6. The NCK SH2 domain binds EPHB1 through Tyr-594. Interacts with PRKCABP.,tissue specificity:Preferentially expressed in brain.,

现货

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.