产品名称
Ankyrin B Rabbit Polyclonal Antibody
别名
Ankyrin-2 (ANK-2) (Ankyrin-B) (Brain ankyrin) (Non-erythroid ankyrin)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=287
Human Swissprot No.
Q01484
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q01484/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/109676
Mouse Swissprot No.
Q8C8R3
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8C8R3
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/0
特异性
This antibody detects endogenous levels of Ankyrin B at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Present in plasma membrane of neurons as well as glial cells throughout the brain. Expressed in fetal brain and in temporal cortex of adult brain. Also expressed in the inner segments of rod photoreceptors in retina.
细胞定位
Cytoplasm, cytoskeleton . Membrane . Cytoplasm, myofibril, sarcomere, M line . Apical cell membrane . Cell membrane . Cell junction, synapse, postsynaptic cell membrane . Early endosome . Recycling endosome . Lysosome . Mitochondrion . Cytoplasm, myofibril, sarcomere, Z line . Cell membrane, sarcolemma, T-tubule . Expressed at the apical membrane of airway lung epithelial cells (By similarity). Localized to the plasma membrane of the inner segments of photoreceptors in retina. Colocalizes with SPTBN1 in a distinct intracellular compartment of neonatal cardiomyocytes (PubMed:19007774). In skeletal muscle, localizes to neuromuscular junctions (By similarity). Localizes with puncta at mitochondria ends. Colocalizes and cotransports on motile vesicles with RABGAP1L (By similarity). .
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
