BD-PT7999

ROR1 Rabbit Polyclonal Antibody

Tyrosine-protein kinase transmembrane receptor ROR1 (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 1)

常规抗体

ROR1 NTRKR1

ROR1

WB

Human,Mouse,Rat

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

4919

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=4919

Q01973

https://www.uniprot.org/uniprotkb/Q01973/entry

26563

https://www.uniprot.org/uniprot/26563

Q9Z139

https://www.uniprot.org/uniprotkb/Q9Z139

https://www.uniprot.org/uniprotkb/0

This antibody detects endogenous levels of ROR1 at Human, Mouse,Rat

WB 1:500-2000

105kD

-15°C to -25°C/1 year(Do not lower than -25°C)

Expressed strongly in human heart, lung and kidney, but weakly in the CNS. Isoform Short is strongly expressed in fetal and adult CNS and in a variety of human cancers, including those originating from CNS or PNS neuroectoderm.

Membrane ; Single-pass type I membrane protein. Cell projection, axon .

catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,developmental stage:Expressed at high levels during early embryonic development. The expression levels drop strongly around day 16 and there are only very low levels in adult tissues.,function:Tyrosine-protein kinase receptor whose role is not yet clear.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily.,similarity:Contains 1 FZ (frizzled) domain.,similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain.,similarity:Contains 1 kringle domain.,similarity:Contains 1 protein kinase domain.,tissue specificity:Expressed strongly in human heart, lung, and kidney, but weakly in the CNS. The short isoform is strongly expressed in fetal and adult CNS and in a variety of human cancers, including those originating from CNS or PNS neuroectoderm.,

现货

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.