产品名称
HSP105 (Phospho-Ser809) Rabbit Polyclonal Antibody
别名
Heat shock protein 105 kDa (Antigen NY-CO-25) (Heat shock 110 kDa protein)
基因名称
HSPH1 HSP105 HSP110 KIAA0201
蛋白名称
HSP105 (Phospho-Ser809)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=10808
Human Swissprot No.
Q92598
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q92598/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/15505
Mouse Swissprot No.
Q61699
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q61699
Rat Gene Link
https://www.uniprot.org/uniprot/288444
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q66HA8
特异性
This antibody detects endogenous levels of HSP105 (Phospho-Ser809) at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Highly expressed in testis. Present at lower levels in most brain regions, except cerebellum. Overexpressed in cancer cells.
功能
function:Prevents the aggregation of denatured proteins in cells under severe stress, on which the ATP levels decrease markedly. Inhibits HSPA8/HSC70 ATPase and chaperone activities.,PTM:Phosphorylation on Ser-509 may be important for regulation of the HSPA8/HSC70 chaperone activity.,similarity:Belongs to the heat shock protein 70 family.,subunit:Interacts with HSPA8/HSC70.,tissue specificity:Highly expressed in testis. Present at lower levels in most brain regions, except cerebellum. Overexpressed in cancer cells.,
纯化
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
