产品名称
MKP-7 (Phospho-Ser446) Rabbit Polyclonal Antibody
别名
Dual specificity protein phosphatase 16 (EC 3.1.3.16) (EC 3.1.3.48) (Mitogen-activated protein kinase phosphatase 7) (MAP kinase phosphatase 7) (MKP-7)
基因名称
DUSP16 KIAA1700 MKP7
蛋白名称
MKP-7 (Phospho-Ser446)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=80824
Human Swissprot No.
Q9BY84
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9BY84/entry
特异性
This antibody detects endogenous levels of MKP-7 (Phospho-Ser446) at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Bone marrow,Brain,Duodenum,PCR rescued clones,
细胞定位
Cytoplasm. Nucleus. Cytoplasmic vesicle. After dissociation upon AGTR stimulation, re-associates with ARRB2 on endocytic vesicles.
功能
catalytic activity:A phosphoprotein + H(2)O = a protein + phosphate.,catalytic activity:Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.,function:Involved in the inactivation of MAP kinases.,similarity:Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.,similarity:Contains 1 rhodanese domain.,similarity:Contains 1 tyrosine-protein phosphatase domain.,
纯化
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
