产品名称
CUTL1 (Phospho-Ser1237) Rabbit Polyclonal Antibody
别名
Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein cux-1)
蛋白名称
CUTL1 (Phospho-Ser1237)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=1523
Human Swissprot No.
P39880
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P39880/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/13047
Mouse Swissprot No.
P53564
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/P53564
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/P53565
特异性
This antibody detects endogenous levels of CUTL1 (Phospho-Ser1237) at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Colon,Duodenum,Liver,Umbilical vein,
功能
alternative products:Additional isoforms seem to exist,function:May be involved in intra-Golgi retrograde transport.,function:Probably has a broad role in mammalian development as a repressor of developmentally regulated gene expression. May act by preventing binding of positively-activing CCAAT factors to promoters. Component of nf-munr repressor; binds to the matrix attachment regions (MARs) (5' and 3') of the immunoglobulin heavy chain enhancer. Represses T-cell receptor (TCR) beta enhancer function by binding to MARbeta, an ATC-rich DNA sequence located upstream of the TCR beta enhancer.,miscellaneous:Asn-1290 may participate in regulating DNA-binding activity by promoting homo- and heterodimerization.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the CASP family.,similarity:Belongs to the CUT homeobox family.,similarity:Contains 1 homeobox DNA-binding domain.,similarity:Contains 3 CUT DNA-binding domains.,subunit:Homodimer; disulfide-linked. Interacts with GOLGA5.,subunit:Interacts with BANP.,
纯化
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
