BD-PN0702

EDEM1 Rabbit Polyclonal Antibody

常规抗体

EDEM1 EDEM KIAA0212

ER degradation-enhancing alpha-mannosidase-like 1

WB

Human,Mouse

1 mg/ml

Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.

9695

Q92611

https://www.uniprot.org/uniprotkb/Q92611/entry

Q925U4

http://www.uniprot.org/uniprot/Q925U4

Synthesized peptide derived from part region of human protein

EDEM1 Polyclonal Antibody detects endogenous levels of protein.

WB 1:500-2000 ELISA 1:5000-20000

72kD

-20°C/1 year

Polyclonal, Rabbit,IgG

function:Extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle. It is directly involved in endoplasmic reticulum-associated degradation (ERAD) and targets misfolded glycoproteins for degradation in an N-glycan-dependent manner. It lacks mannosidase activity.,similarity:Belongs to the glycosyl hydrolase 47 family.,subunit:Interacts with DERL2 and DERL3.,

Bone marrow,Primary B-Cells,Skin,

Endoplasmic reticulum membrane ; Single-pass type II membrane protein .

function:Extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle. It is directly involved in endoplasmic reticulum-associated degradation (ERAD) and targets misfolded glycoproteins for degradation in an N-glycan-dependent manner. It lacks mannosidase activity.,similarity:Belongs to the glycosyl hydrolase 47 family.,subunit:Interacts with DERL2 and DERL3.,

现货

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.