产品名称
VAMP4 (Phospho-Ser30) Rabbit Polyclonal Antibody
别名
Vesicle-associated membrane protein 4 (VAMP-4)
蛋白名称
VAMP4 (Phospho-Ser30)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=8674
Human Swissprot No.
O75379
Human Swissprot Link
https://www.uniprot.org/uniprotkb/O75379/entry
Mouse Swissprot No.
O70480
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/O70480
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/0
特异性
This antibody detects endogenous levels of VAMP4 (Phospho-Ser30) at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
B-cell,Bone marrow,Epithelium,Liver,Urinary bladder,
细胞定位
Golgi apparatus, trans-Golgi network membrane ; Single-pass type IV membrane protein . Associated with trans Golgi network (TGN) and newly formed immature secretory granules (ISG). Not found on the mature secretory organelles.
功能
function:Involved in the pathway that functions to remove an inhibitor (probably synaptotagmin-4) of calcium-triggered exocytosis during the maturation of secretory granules. May be a marker for this sorting pathway that is critical for remodeling the secretory response of granule.,similarity:Belongs to the synaptobrevin family.,similarity:Contains 1 v-SNARE coiled-coil homology domain.,subcellular location:Associated with trans Golgi network (TGN) and newly formed immature secretory granules (ISG). Not found on the mature secretory organelles.,subunit:Identified in a complex containing STX6, STX13, VAMP4 and VTI1A.,
纯化
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
