产品名称
MST3 (Phospho-Thr18) Rabbit Polyclonal Antibody
别名
Serine/threonine-protein kinase 24 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 3) (MST-3) (STE20-like kinase MST3) [Cleaved into: Serine/threonine-protein kinase 24 36 kDa subunit (Mammalian STE20-like protein kinase 3 N-terminal) (MST3/N); Serine/threonine-protein kinase 24 12 kDa subunit (Mammalian STE20-like protein kinase 3 C-terminal) (MST3/C)]
蛋白名称
MST3 (Phospho-Thr18)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=8428
Human Swissprot No.
Q9Y6E0
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9Y6E0/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/223255
Mouse Swissprot No.
Q99KH8
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q99KH8
Rat Gene Link
https://www.uniprot.org/uniprot/361092
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/B0LT89
特异性
This antibody detects endogenous levels of MST3 (Phospho-Thr18) at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Isoform A is ubiquitous. Isoform B is expressed in brain with high expression in hippocampus and cerebral cortex.
细胞定位
Cytoplasm. Nucleus. Membrane. The truncated form (MST3/N) translocates to the nucleus. Colocalizes with STK38L in the membrane.
功能
catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Manganese. Only isoform A requires manganese.,function:Protein kinase that act on both serine and threonine residues.,PTM:Autophosphorylated. Isoform B is activated by phosphorylation by PKA.,similarity:Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.,similarity:Contains 1 protein kinase domain.,tissue specificity:Isoform A is ubiquitous. Isoform B is expressed in brain with high expression in hippocampus and cerebral cortex.,
纯化
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
