产品名称
EIF5 (Phospho-Ser389+Ser390) Rabbit Polyclonal Antibody
别名
Eukaryotic translation initiation factor 5 (eIF-5)
蛋白名称
EIF5 (Phospho-Ser389+Ser390)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=1983
Human Swissprot No.
P55010
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P55010/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/100047658
Mouse Swissprot No.
P59325
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/P59325
Rat Gene Link
https://www.uniprot.org/uniprot/56783
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q07205
特异性
This antibody detects endogenous levels of EIF5 (Phospho-Ser389+Ser390) at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Brain,Epithelium,Lymph,Pooled,Uterus,
细胞定位
nucleus,cytoplasm,cytosol,plasma membrane,cell-cell adherens junction,
功能
function:Catalyzes the hydrolysis of GTP bound to the 40S ribosomal initiation complex (40S.mRNA.Met-tRNA[F].eIF-2.GTP) with the subsequent joining of a 60S ribosomal subunit resulting in the release of eIF-2 and the guanine nucleotide. The subsequent joining of a 60S ribosomal subunit results in the formation of a functional 80S initiation complex (80S.mRNA.Met-tRNA[F]).,similarity:Belongs to the eIF-2-beta/eIF-5 family.,similarity:Contains 1 W2 domain.,
纯化
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.