产品名称
EPHA5 (Phospho-Tyr650) Rabbit Polyclonal Antibody
别名
Ephrin type-A receptor 5 (EC 2.7.10.1) (Brain-specific kinase) (EPH homology kinase 1) (EHK-1) (EPH-like kinase 7) (EK7) (hEK7)
基因名称
EPHA5 BSK EHK1 HEK7 TYRO4
蛋白名称
EPHA5 (Phospho-Tyr650)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=2044
Human Swissprot No.
P54756
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P54756/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/13839
Mouse Swissprot No.
Q60629
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q60629
Rat Gene Link
https://www.uniprot.org/uniprot/79208
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/P54757
特异性
This antibody detects endogenous levels of EPHA5 (Phospho-Tyr650) at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Almost exclusively expressed in the nervous system in cortical neurons, cerebellar Purkinje cells and pyramidal neurons within the cortex and hippocampus. Display an increasing gradient of expression from the forebrain to hindbrain and spinal cord.
细胞定位
Cell membrane ; Single-pass type I membrane protein . Cell projection, axon . Cell projection, dendrite .
功能
alternative products:Additional isoforms seem to exist,catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,function:Receptor for members of the ephrin-A family. Binds to ephrin-A1, -A2, -A3, -A4 and -A5.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 SAM (sterile alpha motif) domain.,similarity:Contains 2 fibronectin type-III domains.,tissue specificity:Almost exclusively expressed in the nervous system.,
纯化
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.