BD-PP1721

c-Fes (Phospho-Tyr713) Rabbit Polyclonal Antibody

Tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (Feline sarcoma/Fujinami avian sarcoma oncogene homolog) (Proto-oncogene c-Fes) (Proto-oncogene c-Fps) (p93c-fes)

常规抗体

FES FPS

c-Fes (Phospho-Tyr713)

WB

Human,Mouse,Rat

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

2242

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=2242

P07332

https://www.uniprot.org/uniprotkb/P07332/entry

14159

https://www.uniprot.org/uniprot/14159

P16879

https://www.uniprot.org/uniprotkb/P16879

https://www.uniprot.org/uniprotkb/0

This antibody detects endogenous levels of c-Fes (Phospho-Tyr713) at Human, Mouse,Rat

WB 1:500-2000

90kD

-15°C to -25°C/1 year(Do not lower than -25°C)

Widely expressed. Detected in adult colon epithelium (at protein level) (PubMed:16455651, PubMed:19051325). Expressed in melanocytes (at protein level) (PubMed:28463229).

Cytoplasm, cytosol. Cytoplasm, cytoskeleton. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle. Golgi apparatus. Cell junction, focal adhesion. Distributed throughout the cytosol when the kinase is not activated. Association with microtubules requires activation of the kinase activity. Shuttles between focal adhesions and cell-cell contacts in epithelial cells. Recruited to the lateral cell membrane in polarized epithelial cells by interaction with phosphorylated EZR. Detected at tubular membrane structures in the cytoplasm and at the cell periphery.

catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily.,similarity:Contains 1 FCH domain.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 SH2 domain.,

现货

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.