产品名称
EF1D Rabbit Polyclonal Antibody
蛋白名称
Elongation factor 1-delta (EF-1-delta) (Antigen NY-CO-4)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
P29692
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P29692/entry
Mouse Swissprot No.
P57776
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P57776
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941Q68FR9
免疫原
Synthesized peptide derived from part region of human protein
特异性
EF1D Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
eukaryotic translation elongation factor 1 delta(EEF1D) Homo sapiens This gene encodes a subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This subunit, delta, functions as guanine nucleotide exchange factor. It is reported that following HIV-1 infection, this subunit interacts with HIV-1 Tat. This interaction results in repression of translation of host cell proteins and enhanced translation of viral proteins. Several alternatively spliced transcript variants encoding multiple isoforms have been found for this gene. Related pseudogenes have been defined on chromosomes 1, 6, 7, 9, 11, 13, 17, 19.[provided by RefSeq, Aug 2010],
组织表达
Isoform 2 is specifically expressed in brain, cerebellum and testis.
细胞定位
[Isoform 2]: Nucleus .
功能
function:EF-1-beta and EF-1-delta stimulate the exchange of GDP bound to EF-1-alpha to GTP.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the EF-1-beta/EF-1-delta family.,subunit:EF-1 is composed of 4 subunits: alpha, beta, delta, and gamma.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
