产品名称
BLK (Phospho-Tyr389) Rabbit Polyclonal Antibody
别名
Tyrosine-protein kinase Blk (EC 2.7.10.2) (B lymphocyte kinase) (p55-Blk)
蛋白名称
BLK (Phospho-Tyr389)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=640
Human Swissprot No.
P51451
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P51451/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/12143
Mouse Swissprot No.
P16277
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/P16277
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/0
特异性
This antibody detects endogenous levels of BLK (Phospho-Tyr389) at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Expressed in lymphatic organs, pancreatic islets, Leydig cells, striate ducts of salivary glands and hair follicles.
细胞定位
Cell membrane ; Lipid-anchor . Present and active in lipid rafts. Membrane location is required for the phosphorylation of CD79A and CD79B (By similarity). .
功能
catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,function:May function in a signal transduction pathway that is restricted to B-lymphoid cells.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 SH2 domain.,similarity:Contains 1 SH3 domain.,
纯化
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
