产品名称
EPHB4 (Phospho-Tyr987) Rabbit Polyclonal Antibody
别名
Ephrin type-B receptor 4 (EC 2.7.10.1) (Hepatoma transmembrane kinase) (Tyrosine-protein kinase TYRO11)
基因名称
EPHB4 HTK MYK1 TYRO11
蛋白名称
EPHB4 (Phospho-Tyr987)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=2050
Human Swissprot No.
P54760
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P54760/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/13846
Mouse Swissprot No.
P54761
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/P54761
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/0
特异性
This antibody detects endogenous levels of EPHB4 (Phospho-Tyr987) at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Abundantly expressed in placenta but also detected in kidney, liver, lung, pancreas, skeletal muscle and heart. Expressed in primitive and myeloid, but not lymphoid, hematopoietic cells. Also observed in cell lines derived from liver, breast, colon, lung, melanocyte and cervix.
细胞定位
Cell membrane ; Single-pass type I membrane protein .
功能
catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,function:Receptor for members of the ephrin-B family. Binds to ephrin-B2. May have a role in events mediating differentiation and development.,PTM:Autophosphorylated.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 SAM (sterile alpha motif) domain.,similarity:Contains 2 fibronectin type-III domains.,tissue specificity:Abundantly expressed in placenta and in a range of primary tissues and malignant cell lines. Expressed in fetal, but not adult, brain, and in primitive and myeloid, but not lymphoid, hematopoietic cells.,
纯化
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
