BD-PP1681

L-plastin (Phospho-Ser5) Rabbit Polyclonal Antibody

Plastin-2 (L-plastin) (LC64P) (Lymphocyte cytosolic protein 1) (LCP-1)

常规抗体

LCP1 PLS2

L-plastin (Phospho-Ser5)

WB

Human,Mouse,Rat

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

3936

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=3936

P13796

https://www.uniprot.org/uniprotkb/P13796/entry

18826

https://www.uniprot.org/uniprot/18826

Q61233

https://www.uniprot.org/uniprotkb/Q61233

https://www.uniprot.org/uniprotkb/0

This antibody detects endogenous levels of L-plastin (Phospho-Ser5) at Human, Mouse,Rat

WB 1:500-2000

69kD

-15°C to -25°C/1 year(Do not lower than -25°C)

Detected in intestinal microvilli, hair cell stereocilia, and fibroblast filopodia, in spleen and other lymph node-containing organs. Expressed in peripheral blood T-lymphocytes, neutrophils, monocytes, B-lymphocytes, and myeloid cells.

Cytoplasm, cytoskeleton . Cell junction . Cell projection . Cell projection, ruffle membrane ; Peripheral membrane protein ; Cytoplasmic side . Relocalizes to the immunological synapse between peripheral blood T-lymphocytes and antibody-presenting cells in response to costimulation through TCR/CD3 and CD2 or CD28 (PubMed:17294403). Associated with the actin cytoskeleton at membrane ruffles. Relocalizes to actin-rich cell projections upon serine phosphorylation (PubMed:16636079). .

function:Actin-binding protein found in intestinal microvilli, hair cell stereocilia, and fibroblast filopodia.,PTM:Phosphorylated.,PTM:The N-terminus is blocked.,similarity:Contains 2 actin-binding domains.,similarity:Contains 2 EF-hand domains.,similarity:Contains 4 CH (calponin-homology) domains.,subunit:Monomer.,tissue specificity:Restricted to the spleen and other lymph node-containing organs. Expressed in neutrophils, monocytes, B lymphocytes, and myeloid cells.,

现货

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.