产品名称
FGR (Phospho-Tyr412) Rabbit Polyclonal Antibody
别名
Tyrosine-protein kinase Fgr (EC 2.7.10.2) (Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog) (Proto-oncogene c-Fgr) (p55-Fgr) (p58-Fgr) (p58c-Fgr)
蛋白名称
FGR (Phospho-Tyr412)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=2268
Human Swissprot No.
P09769
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P09769/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/14191
Mouse Swissprot No.
P14234
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/P14234
Rat Gene Link
https://www.uniprot.org/uniprot/79113
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q6P6U0
特异性
This antibody detects endogenous levels of FGR (Phospho-Tyr412) at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Detected in neutrophils, monocytes and natural killer cells (at protein level). Detected in monocytes and large lymphocytes.
细胞定位
Cell membrane ; Lipid-anchor ; Cytoplasmic side . Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, ruffle membrane. Cytoplasm, cytosol. Cytoplasm, cytoskeleton. Mitochondrion inner membrane . Mitochondrion intermembrane space . Detected in mitochondrial intermembrane space and at inner membranes (By similarity). Colocalizes with actin fibers at membrane ruffles. Detected at plasma membrane lipid rafts. .
功能
catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 SH2 domain.,similarity:Contains 1 SH3 domain.,subunit:Binds PTPNS1.,
纯化
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
