BD-PM4117

Insulin(PT0156)Mouse Monoclonal Antibody

Insulin [Cleaved into: Insulin B chain; Insulin A chain]

常规抗体

INS

Insulin

WB

Human, Mouse (predicted: Rat)

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

3630

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=3630

P01308

https://www.uniprot.org/uniprotkb/P01308/entry

This antibody detects endogenous levels of Insulin at Human

IHC-p 1:200-400, WB 1:200-1000

-15°C to -25°C/1 year(Do not lower than -25°C)

Cytoplasmic

Secreted.

disease:Defects in INS are the cause of familial hyperproinsulinemia [MIM:176730].,function:Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.,function:Preptin undergoes glucose-mediated co-secretion with insulin, and acts as physiological amplifier of glucose-mediated insulin secretion. Exhibits osteogenic properties by increasing osteoblast mitogenic activity through phosphoactivation of MAPK1 and MAPK3.,function:The insulin-like growth factors possess growth-promoting activity. In vitro, they are potent mitogens for cultured cells. IGF-II is influenced by placental lactogen and may play a role in fetal development.,mass spectrometry: PubMed:12586351; PubMed:15359740,online information:Clinical information on Eli Lilly insulin products,online information:Insulin entry,online information:Insulin-like growth factor 2 entry,online information:Protein of the 20th century - Issue 9 of April 2001,pharmaceutical:Available under the names Humulin or Humalog (Eli Lilly) and Novolin (Novo Nordisk). Used in the treatment of diabetes. Humalog is an insulin analog with 52-Lys-Pro-53 instead of 52-Pro-Lys-53.,similarity:Belongs to the insulin family.,subunit:Heterodimer of a B chain and an A chain linked by two disulfide bonds.,

现货

The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.