BD-PN5653

CACNB3 Rabbit Polyclonal Antibody

CACNB3; CACNLB3; Voltage-dependent L-type calcium channel subunit beta-3; CAB3; Calcium channel voltage-dependent subunit beta 3

常规抗体

CACNB3

Voltage-dependent L-type calcium channel subunit beta-3

WB

Mouse,Rat

PBS, pH 7.4, containing 0.5%BSA, 0.02% New type preservative N as Preservative and 50% Glycerol.

784

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=784

P54284

http://www.uniprot.org/uniprotkb/P54284/entry

P54285

http://www.uniprot.org/uniprot/P54285

P54287

http://www.uniprot.org/uniprot/O54941P54287

Synthetic Peptide of CACNB3

The antibody detects endogenous CACNB3 protein.

WB 1:500-1000 IHC 1:200-500. IF 1:50-200

50kD

-20°C/1 year

Polyclonal, Rabbit,IgG

This gene encodes a regulatory beta subunit of the voltage-dependent calcium channel. Beta subunits are composed of five domains, which contribute to the regulation of surface expression and gating of calcium channels and may also play a role in the regulation of transcription factors and calcium transport. [provided by RefSeq, Oct 2011],

Expressed mostly in brain, colon and ovary.

Cytoplasm .

MAPK_ERK_Growth;MAPK_G_Protein;Cardiac muscle contraction;Hypertrophic cardiomyopathy (HCM);Arrhythmogenic right ventricular cardiomyopathy (ARVC);Dilated cardiomyopathy;

function:The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting.,similarity:Belongs to the calcium channel beta subunit family.,similarity:Contains 1 SH3 domain.,subunit:The L-type calcium channel is composed of four subunits: alpha-1, alpha-2, beta and gamma. Interacts with CACNA2D4.,tissue specificity:Expressed mostly in brain, smooth muscle and ovary.,

现货

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.