产品名称
Mas1 Rabbit Polyclonal Antibody
别名
MAS1; MAS; Proto-oncogene Mas
存储缓冲液
PBS, pH 7.4, containing 0.5%BSA, 0.02% New type preservative N as Preservative and 50% Glycerol.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=4142
Human Swissprot No.
P04201
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P04201/entry
Mouse Swissprot No.
P30554
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P30554
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941P12526
免疫原
Synthetic Peptide of Mas1
特异性
The antibody detects endogenous Mas1 protein.
稀释度
WB 1:2000-5000 IHC 1:200-500. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a class I seven-transmembrane G-protein-coupled receptor. The encoded protein is a receptor for angiotensin-(1-7) and preferentially couples to the Gq protein, activating the phospholipase C signaling pathway. The encoded protein may play a role in multiple processes including hypotension, smooth muscle relaxation and cardioprotection by mediating the effects of angiotensin-(1-7). [provided by RefSeq, May 2012],
细胞定位
Cell membrane ; Multi-pass membrane protein .
信号通路
Neuroactive ligand-receptor interaction;Renin-angiotensin system;
功能
caution:Was originally (PubMed:3419518) thought to be a receptor for angiotensin II.,disease:The MAS oncogene has a weak focus-inducing activity in transfected NIH 3T3 cells.,similarity:Belongs to the G-protein coupled receptor 1 family.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
