BD-PP1636

PEPC (Phospho Ser15) Rabbit Polyclonal Antibody

PGC; Gastricsin; Pepsinogen C

常规抗体

PGC

Gastricsin

WB

Plants

PBS, pH 7.4, containing 0.5%BSA, 0.02% New type preservative N as Preservative and 50% Glycerol.

5225

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=5225

P20142

http://www.uniprot.org/uniprotkb/P20142/entry

109820

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=109820

Q9D7R7

http://www.uniprot.org/uniprot/Q9D7R7

24864

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=24864

P04073

http://www.uniprot.org/uniprot/P04073

Synthetic Peptide of PEPC (Phospho Ser15)

The antibody detects endogenous PEPC (Phospho Ser15) protein.

WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000

105-110kD

-20°C/1 year

Polyclonal, Rabbit,IgG

This gene encodes an aspartic proteinase that belongs to the peptidase family A1. The encoded protein is a digestive enzyme that is produced in the stomach and constitutes a major component of the gastric mucosa. This protein is also secreted into the serum. This protein is synthesized as an inactive zymogen that includes a highly basic prosegment. This enzyme is converted into its active mature form at low pH by sequential cleavage of the prosegment that is carried out by the enzyme itself. Polymorphisms in this gene are associated with susceptibility to gastric cancers. Serum levels of this enzyme are used as a biomarker for certain gastric diseases including Helicobacter pylori related gastritis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 1. [provided by RefSeq, Oct 2009],

Brain,Liver,Placenta,Stomach,

Secreted.

catalytic activity:More restricted specificity than pepsin A, but shows preferential cleavage at Tyr-|-Xaa bonds. High activity on hemoglobin.,function:Hydrolyzes a variety of proteins.,similarity:Belongs to the peptidase A1 family.,

现货

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.