产品名称
LDHD Rabbit Polyclonal Antibody
别名
Probable D-lactate dehydrogenase, mitochondrial (DLD) (Lactate dehydrogenase D) (EC 1.1.2.4)
蛋白名称
Probable D-lactate dehydrogenase, mitochondrial
存储缓冲液
PBS, pH 7.4, containing 0.5%BSA, 0.02% New type preservative N as Preservative and 50% Glycerol.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=197257
Human Swissprot No.
Q86WU2
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q86WU2/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=52815
Mouse Swissprot No.
Q7TNG8
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q7TNG8
Rat Swissprot Link
http://www.uniprot.org/uniprot/
免疫原
Recombinant Protein of LDHD
特异性
The antibody detects endogenous LDHD protein.
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. The similar protein in yeast has both D-lactate and D-glycerate dehydrogenase activities. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Jul 2008],
组织表达
Expressed moderately in heart and liver and at lower levels in skeletal muscle and kidney.
信号通路
Pyruvate metabolism;
功能
catalytic activity:(R)-lactate + 2 ferricytochrome c = pyruvate + 2 ferrocytochrome c.,cofactor:FAD.,similarity:Belongs to the FAD-binding oxidoreductase/transferase type 4 family.,similarity:Contains 1 FAD-binding PCMH-type domain.,subunit:Interacts with CSRP3.,tissue specificity:Expressed moderately in heart and liver and at lower levels in skeletal muscle and kidney.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
