产品名称
Eif4b Rabbit Polyclonal Antibody
别名
Eukaryotic translation initiation factor 4B (eIF-4B)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.77% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/1975
Human Swissprot No.
P23588
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P23588/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/75705
Mouse Swissprot No.
Q8BGD9
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8BGD9
免疫原
Synthesized peptide derived from human Eif4b AA range: 209-259
特异性
This antibody detects endogenous levels of Eif4b at Human, Mouse,Rat
稀释度
IHC-p1:50-200 ,WB 1:1000-2000
宿主
Polyclonal, Rabbit,IgG
背景介绍
cRequired for the binding of mRNA to ribosomes. Functions in close association with EIF4-F and EIF4-A. Binds near the 5'-terminal cap of mRNA in presence of EIF-4F and ATP. Promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both EIF4-A and EIF4-F.,similarity:Contains 1 RRM (RNA recognition motif) domain.,subunit:Self-associates and interacts with EIF3 p170 subunit.
组织表达
Adipose tissue,Brain,Cervix carcinoma,Epithelium,Liver,Lung
细胞定位
cytosol,polysome,eukaryotic translation initiation factor 4F complex,dendrite,neuronal cell body,
功能
function:Required for the binding of mRNA to ribosomes. Functions in close association with EIF4-F and EIF4-A. Binds near the 5'-terminal cap of mRNA in presence of EIF-4F and ATP. Promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both EIF4-A and EIF4-F.,similarity:Contains 1 RRM (RNA recognition motif) domain.,subunit:Self-associates and interacts with EIF3 p170 subunit.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
