产品名称
PDK4 Rabbit Polyclonal Antibody
别名
[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 4, mitochondrial (EC 2.7.11.2) (Pyruvate dehydrogenase kinase isoform 4)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.03% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/5166
Human Swissprot No.
Q16654
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q16654/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/27273
Mouse Swissprot No.
O70571
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/O70571
Rat Gene Link
https://www.uniprot.org/uniprot/89813
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/O54937
免疫原
Synthesized peptide derived from human PDK4 AA range: 34-84
特异性
This antibody detects endogenous levels of PDK4 at Human, Mouse,Rat
稀释度
IHC-p1:50-200 ,WB 1:1000-2000
宿主
Polyclonal, Rabbit,IgG
背景介绍
Pyruvate dehydrogenase kinase isoform4 (PDK4) is also named as PDHK4 and belongs to the PDK/BCKDK protein kinase family. It is upregulated by starvation in many tissues of the body during starvation. This causes inactivation of the pyruvate dehydrogenase complex which blocks pyruvate oxidation and conserves lactate and alanine for gluconeogenesis.
组织表达
Ubiquitous; highest levels of expression in heart and skeletal muscle.
细胞定位
Mitochondrion matrix.
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
