产品名称
EFHD1 Rabbit Polyclonal Antibody
别名
EF-hand domain-containing protein D1 (EF-hand domain-containing protein 1) (Swiprosin-2)
蛋白名称
EF-hand domain-containing protein D1
存储缓冲液
PBS, pH 7.4, containing 0.5%BSA, 0.02% New type preservative N as Preservative and 50% Glycerol.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=80303
Human Swissprot No.
Q9BUP0
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q9BUP0/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=98363
Mouse Swissprot No.
Q9D4J1
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9D4J1
Rat Swissprot Link
http://www.uniprot.org/uniprot/
免疫原
Recombinant Protein of EF-hand domain-containing protein D1
特异性
The antibody detects endogenous EFHD1 proteins.
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the EF-hand super family of calcium binding proteins, which are involved in a variety of cellular processes including mitosis, synaptic transmission, and cytoskeletal rearrangement. The protein encoded by this gene is composed of an N-terminal disordered region, proline-rich elements, two EF-hands, and a C-terminal coiled-coil domain. This protein has been shown to associate with the mitochondrial inner membrane, and in HeLa cells, acts as a novel mitochondrial calcium ion sensor for mitochondrial flash activation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2016],
组织表达
Brain,Eye,Heart,Hippocampus,Lung,Normal aorta,Placenta,
细胞定位
Mitochondrion inner membrane .
功能
similarity:Contains 2 EF-hand domains.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.