产品名称
RNF41 Rabbit Polyclonal Antibody
基因名称
RNF41 FLRF NRDP1 SBBI03
蛋白名称
E3 ubiquitin-protein ligase NRDP1 (EC 6.3.2.-) (RING finger protein 41)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q9H4P4
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9H4P4/entry
Mouse Swissprot No.
Q8BH75
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8BH75
免疫原
Synthesized peptide derived from part region of human protein
特异性
RNF41 Polyclonal Antibody detects endogenous levels of protein.
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes an E3 ubiquitin ligase. The encoded protein plays a role in type 1 cytokine receptor signaling by controlling the balance between JAK2-associated cytokine receptor degradation and ectodomain shedding. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2011],
组织表达
Detected in ovary, testis and prostate.
功能
function:Acts as E3 ubiquitin-protein ligase and regulates the degradation of target proteins, such as ERBB3.,pathway:Protein modification; protein ubiquitination.,PTM:Autoubiquitinated.,similarity:Contains 1 RING-type zinc finger.,similarity:Contains 1 SIAH-type zinc finger.,subunit:Interacts with USP8 and ERBB3.,tissue specificity:Detected in ovary, testis and prostate.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.