产品名称
RPOM Rabbit Polyclonal Antibody
蛋白名称
DNA-directed RNA polymerase, mitochondrial (MtRPOL) (EC 2.7.7.6)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
O00411
Human Swissprot Link
https://www.uniprot.org/uniprotkb/O00411/entry
Mouse Swissprot No.
Q8BKF1
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8BKF1
免疫原
Synthesized peptide derived from part region of human protein
特异性
RPOM Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a mitochondrial DNA-directed RNA polymerase. The gene product is responsible for mitochondrial gene expression as well as for providing RNA primers for initiation of replication of the mitochondrial genome. Although this polypeptide has the same function as the three nuclear DNA-directed RNA polymerases, it is more closely related to RNA polymerases of phage and mitochondrial polymerases of lower eukaryotes. [provided by RefSeq, Jul 2008],
组织表达
Aorta endothelial cell,Brain,Liver,
功能
catalytic activity:Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).,function:DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.,similarity:Belongs to the phage and mitochondrial RNA polymerase family.,subunit:Interacts with TFB1M and TFB2M, leading to the stimulation of transcription.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
