产品名称
PSM Rabbit Polyclonal Antibody
别名
Glutamate carboxypeptidase 2 (EC 3.4.17.21;Cell growth-inhibiting gene 27 protein;Folate hydrolase 1;Folylpoly-gamma-glutamate carboxypeptidase;FGCP;Glutamate carboxypeptidase II;GCPII;Membrane glutamate carboxypeptidase;mGCP;N-acetylated-alpha-linked acidic dipeptidase I;NAALADase I;Prostate-specific membrane antigen;PSM;PSMA;Pteroylpoly-gamma-glutamate carboxypeptidase)
基因名称
FOLH1 FOLH NAALAD1 PSM PSMA GIG27
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/2346
Human Swissprot No.
Q04609
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q04609/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/53320
Mouse Swissprot No.
O35409
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/O35409
Rat Gene Link
https://www.uniprot.org/uniprot/85309
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/P70627
免疫原
Synthesized peptide derived from human PSM AA range: 571-620
特异性
This antibody detects endogenous levels of Human PSM
稀释度
WB 1:500-2000;IHC-p 1:50-300
宿主
Polyclonal, Rabbit,IgG
组织表达
Highly expressed in prostate epithelium. Detected in urinary bladder, kidney, testis, ovary, fallopian tube, breast, adrenal gland, liver, esophagus, stomach, small intestine, colon and brain (at protein level). Detected in the small intestine, brain, kidney, liver, spleen, colon, trachea, spinal cord and the capillary endothelium of a variety of tumors. Expressed specifically in jejunum brush border membranes. In the brain, highly expressed in the ventral striatum and brain stem. Also expressed in fetal liver and kidney. Isoform PSMA' is the most abundant form in normal prostate. Isoform PSMA-1 is the most abundant form in primary prostate tumors. Isoform PSMA-3 is also found in normal prostate as well as in brain and liver. Isoform PSMA-9 is specifically expressed in prostate cancer.
细胞定位
Cell membrane ; Single-pass type II membrane protein .; [Isoform PSMA']: Cytoplasm .
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
