产品名称
SAA2 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/6289
Human Swissprot No.
P0DJI9
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P0DJI9/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/20209
Mouse Swissprot No.
P05367
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/P05367
免疫原
Synthesized peptide derived from human SAA2 AA range: 36-86
特异性
This antibody detects endogenous levels of SAA2 at Human/Mouse
宿主
Polyclonal, Rabbit,IgG
组织表达
Expressed by the liver; secreted in plasma.
功能
disease:BOL is from a patient with Waldenstrom macroglobulinemia.,disease:JL is from a patient with ankylosing spondylitis.,disease:Reactive, secondary amyloidosis is characterized by the extracellular accumulation in various tissues of the SAA protein. These deposits are highly insoluble and resistant to proteolysis; they disrupt tissue structure and compromise function.,disease:TH is from a patient with juvenile rheumatoid arthritis.,function:Major acute phase reactant. Apolipoprotein of the HDL complex.,induction:Upon cytokine stimulation.,mass spectrometry: PubMed:12606051,mass spectrometry: PubMed:12973732,mass spectrometry:With variant Ala-70 PubMed:1463770,mass spectrometry:With variants Ala-70, Val-75, Asn-78 and 86-Leu-Thr-87 PubMed:1463770,miscellaneous:Elevated serum SSA protein levels may be associated with lung cancer.,polymorphism:Both SAA1 and SAA2 have a number of alleles. We use here the nomenclature of PubMed:1546977. The sequence shown is that of 1-alpha.,PTM:This protein is the precursor of amyloid protein A, which is formed by the removal of approximately 24 residues from the C-terminal end.,similarity:Belongs to the SAA family.,tissue specificity:Expressed by the liver; secreted in plasma.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
