产品名称
Claudin-18 Rabbit Polyclonal Antibody
基因名称
CLDN18 UNQ778/PRO1572
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/51208
Human Swissprot No.
P56856
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P56856/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/56492
Mouse Swissprot No.
P56857
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/P56857
免疫原
Synthesized peptide derived from human Claudin-18. AA:70-100
特异性
This antibody detects endogenous levels of Human Claudin-18
稀释度
WB 1:1000-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
组织表达
Isoform A1: Expression is restricted to the lung (PubMed:19047087). Isoform A2: Expression is restricted to the stomach mucosa where it is predominantly observed in the epithelial cells of the pit region and the base of the gastric glands including exocrine and endocrine cells (at protein level) (PubMed:19047087).
细胞定位
Cell junction, tight junction . Cell membrane ; Multi-pass membrane protein . Localizes to tight junctions in epithelial cells. .
功能
function:Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.,similarity:Belongs to the claudin family.,tissue specificity:Concentrated at the cell-cell borders of epithelial cells.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
