产品名称
GROβ Rabbit Polyclonal Antibody
别名
C-X-C motif chemokine 2 (Growth-regulated protein beta;Gro-beta;Macrophage inflammatory protein 2-alpha;MIP2-alpha) [Cleaved into: GRO-beta(5-73;GRO-beta-T;Hematopoietic synergistic factor;HSF;SB-251353)]
基因名称
CXCL2 GRO2 GROB MIP2A SCYB2
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/2920
Human Swissprot No.
P19875
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P19875/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/20310
Mouse Swissprot No.
P10889
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/P10889
Rat Gene Link
https://www.uniprot.org/uniprot/114105
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/P30348
免疫原
Synthesized peptide derived from human GROβ AA range: 58-107
特异性
This antibody detects endogenous levels of Human GROβ
稀释度
WB 1:1000-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
function:Produced by activated monocytes and neutrophils and expressed at sites of inflammation. Hematoregulatory chemokine, which, in vitro, suppresses hematopoietic progenitor cell proliferation. GRO-beta(5-73) shows a highly enhanced hematopoietic activity.,online information:CXCL2 entry,pharmaceutical:GRO-beta(5-73) is available under the name Garnocestim as immunomodulator. It is used prior to hematopoietic transplantation for peripheral blood stem cell mobilization and reduction of incidence, duration, and/or severity of chemotherapy induced cytopenias.,PTM:The N-terminal processed form GRO-beta(5-73) is produced by proteolytic cleavage after secretion from bone marrow stromal cells.,similarity:Belongs to the intercrine alpha (chemokine CxC) family.,
功能
chemotaxis,?defense response,?inflammatory response,?immune response,?cell surface receptor linked signal transduction,?G-protein coupled receptor protein signaling pathway,?behavior,?locomotory behavior,?response to wounding,?taxis,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
