产品名称
IL-17 Rabbit Polyclonal Antibody
别名
Interleukin-17A (IL-17;IL-17A;Cytotoxic T-lymphocyte-associated antigen 8;CTLA-8)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/3605
Human Swissprot No.
Q16552
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q16552/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/16171
Mouse Swissprot No.
Q62386
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q62386
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q61453
免疫原
Synthesized peptide derived from human IL-17 AA range: 50-100
特异性
This antibody detects endogenous levels of Human IL-17
稀释度
WB 1:500-2000;Flow Cyt 1:50-200; ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
function:Induces stromal cells to produce proinflammatory and hematopoietic cytokines. Enhances the surface expression of the intracellular adhesion molecule-1 (ICAM-1) in fibroblasts.,online information:Interleukin-17 entry,PTM:Found both in glycosylated and nonglycosylated forms.,similarity:Belongs to the IL-17 family.,subunit:Homodimer.,tissue specificity:Restricted to activated memory T-cells.,
组织表达
Expressed in memory Th17 cells (at protein level).
功能
regulation of transcription, DNA-dependent,?regulation of transcription from RNA polymerase II promoter,?protein amino acid glycosylation,?apoptosis,?defense response,?inflammatory response,?immune response,?cell-cell signaling,cell death,?glycoprotein metabolic process,?glycoprotein biosynthetic process,?response to wounding,?positive regulation of biosynthetic process,?positive regulation of macromolecule biosynthetic process,?positive regulation of macromolecule metabolic process,?positive regulation of gene expression,?programmed cell death,?death,?positive regulation of cellular biosynthetic process,?biopolymer glycosylation,?regulation of transcription,?positive regulation of transcription, DNA-dependent,?positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process,?positive regulation of transcription,?positive regulation of transcription from RNA polymerase II promoter,positive regulation of nitrogen compound metabolic process,?regulation of RNA metabolic process,?positive regulation of RNA metabolic process,?glycosylation,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
