产品名称
A-FABP Rabbit Polyclonal Antibody
别名
Fatty acid-binding protein, adipocyte (Adipocyte lipid-binding protein;ALBP;Adipocyte-type fatty acid-binding protein;A-FABP;AFABP;Fatty acid-binding protein 4)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/2167
Human Swissprot No.
P15090
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P15090/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/11770
Mouse Swissprot No.
P04117
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/P04117
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/P70623
免疫原
Synthesized peptide derived from human A-FABP AA range: 80-120
特异性
This antibody detects endogenous levels of Human A-FABP
稀释度
WB 1:1000-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
FABP4 encodes the fatty acid binding protein found in adipocytes. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. It is thought that FABPs roles include fatty acid uptake, transport, and metabolism. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasm . Nucleus . Depending on the nature of the ligand, a conformation change exposes a nuclear localization motif and the protein is transported into the nucleus. Subject to constitutive nuclear export. .
功能
domain:Forms a beta-barrel structure that accommodates hydrophobic ligands in its interior.,function:Lipid transport protein in adipocytes. Binds both long chain fatty acids and retinoic acid. Delivers long-chain fatty acids and retinoic acid to their cognate receptors in the nucleus.,similarity:Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.,subcellular location:Depending on the nature of the ligand, a conformation change exposes a nuclear localization motif and the protein is transported into the nucleus. Subject to constitutive nuclear export.,subunit:Homodimer. Interacts with PPARG (By similarity). Monomer.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
