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ANGPTL3 Rabbit Polyclonal Antibody

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产品基本信息

产品货号
BD-PT7793
产品名称
ANGPTL3 Rabbit Polyclonal Antibody
别名
Angiopoietin-related protein 3 (Angiopoietin-5;ANG-5;Angiopoietin-like protein 3)
类别
常规抗体
基因名称
ANGPTL3 ANGPT5 UNQ153/PRO179
蛋白名称
ANGPTL3
推荐应用
WB
反应种属
Human,Rat,Mouse
浓度
1 mg/ml
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene ID
27329
Human Gene Link
https://www.uniprot.org/uniprot/27329
Human Swissprot No.
Q9Y5C1
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9Y5C1/entry
Mouse Gene ID
30924
Mouse Gene Link
https://www.uniprot.org/uniprot/30924
Mouse Swissprot No.
Q9R182
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9R182
免疫原
Synthesized peptide derived from human ANGPTL3 AA range: 50-130
特异性
This antibody detects endogenous levels of Human ANGPTL3
稀释度
WB 1:1000-2000 ELISA 1:5000-20000
参考分子量
51kD
运输及保存条件
-20°C/1 year
宿主
Polyclonal, Rabbit,IgG
背景介绍
similarity:Contains 1 fibrinogen C-terminal domain.,tissue specificity:Expressed principally in liver. Weakly expressed in kidney.,
组织表达
Expressed principally in liver. Weakly expressed in kidney. Binds to adipocytes. Increased expression and colocalization with activated ITGB3 in glomeruli of patients with nephrotic syndrome showing effaced podocyte foot processes (at protein level).
细胞定位
Secreted . Cell projection, lamellipodium . Colocalized with HSPG2 and activated ITGB3 on podocytes. .
功能
blood vessel development,?vasculature development,?glycerol metabolic process,?fatty acid metabolic process,phospholipid metabolic process,?cell adhesion,?cell-matrix adhesion,?cell surface receptor linked signal transduction,integrin-mediated signaling pathway,?steroid metabolic process,?cholesterol metabolic process,?phospholipid catabolic process,?regulation of catabolic process,?positive regulation of catabolic process,?regulation of phospholipase activity,negative regulation of phospholipase activity,?lipid localization,?lipid catabolic process,?sterol metabolic process,regulation of lipid metabolic process,?alditol metabolic process,?organophosphate metabolic process,?polyol metabolic process,?lipid storage,?biological adhesion,?regulation of cell migration,?positive regulation of cell migration,?cell-substrate adhesion,?regulation of locomotion,?positive regulation of locomotion,?homeostatic process,?cholesterol homeostasis,?negative regulation of catalytic activity,?negative regulation of molecular function,?cellular lipid catabolic process,?regulation of angiogenesis,?positive regulation of angiogenesis,?positive regulation of lipid metabolic process,blood vessel morphogenesis,?artery morphogenesis,?chemical homeostasis,?regulation of lipid catabolic process,positive regulation of lipid catabolic process,?regulation of lipoprotein lipase activity,?negative regulation of lipoprotein lipase activity,?positive regulation of developmental process,?regulation of cell motion,?positive regulation of cell motion,?regulation of hydrolase activity,?negative regulation of hydrolase activity,?lipid homeostasis,?acylglycerol homeostasis,?phospholipid homeostasis,?sterol homeostasis,?regulation of lipase activity,?negative regulation of lipase activity,
期货
现货
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

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