产品名称
AMPKβ2 Rabbit Polyclonal Antibody
别名
5'-AMP-activated protein kinase subunit beta-2 (AMPK subunit beta-2)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/5565
Human Swissprot No.
O43741
Human Swissprot Link
https://www.uniprot.org/uniprotkb/O43741/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/108097
Mouse Swissprot No.
Q6PAM0
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q6PAM0
Rat Gene Link
https://www.uniprot.org/uniprot/64562
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q9QZH4
免疫原
Synthesized peptide derived from human AMPKβ2 AA range: 130-210
特异性
This antibody detects endogenous levels of Human AMPKβ2
稀释度
WB 1:1000-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
function:AMPK is responsible for the regulation of fatty acid synthesis by phosphorylation of acetyl-CoA carboxylase. Also regulates cholesterol synthesis via phosphorylation and inactivation of hydroxymethylglutaryl-CoA reductase and hormone-sensitive lipase. This is a regulatory subunit, may be a positive regulator of AMPK activity. It may also serve as an adapter molecule for the catalytic alpha-subunit.,PTM:Phosphorylated when associated with the catalytic subunit.,similarity:Belongs to the 5'-AMP-activated protein kinase beta subunit family.,subunit:Heterotrimer of an alpha catalytic subunit, a beta and a gamma non-catalytic regulatory subunits.,
功能
fatty acid metabolic process,?fatty acid biosynthetic process,?lipid biosynthetic process,?regulation of cellular ketone metabolic process,?organic acid biosynthetic process,?regulation of lipid metabolic process,?regulation of fatty acid metabolic process,?regulation of fatty acid oxidation,?carboxylic acid biosynthetic process,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
