产品名称
3MG Rabbit Polyclonal Antibody
蛋白名称
DNA-3-methyladenine glycosylase (EC 3.2.2.21) (3-alkyladenine DNA glycosylase) (3-methyladenine DNA glycosidase) (ADPG) (N-methylpurine-DNA glycosylase)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
P29372
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P29372/entry
Mouse Swissprot No.
Q04841
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q04841
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941P23571
免疫原
Synthesized peptide derived from part region of human protein
特异性
3MG Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
alternative products:Experimental confirmation may be lacking for some isoforms,catalytic activity:Hydrolysis of alkylated DNA, releasing 3-methyladenine, 3-methylguanine, 7-methylguanine and 7-methyladenine.,function:Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, and 7-methylguanine from the damaged DNA polymer formed by alkylation lesions.,similarity:Belongs to the DNA glycosylase MPG family.,subunit:Binds MBD1.,
组织表达
Epithelium,Liver,Pancreas,
细胞定位
Cytoplasm . Mitochondrion matrix, mitochondrion nucleoid . Nucleus .
信号通路
Base excision repair;
功能
alternative products:Experimental confirmation may be lacking for some isoforms,catalytic activity:Hydrolysis of alkylated DNA, releasing 3-methyladenine, 3-methylguanine, 7-methylguanine and 7-methyladenine.,function:Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, and 7-methylguanine from the damaged DNA polymer formed by alkylation lesions.,similarity:Belongs to the DNA glycosylase MPG family.,subunit:Binds MBD1.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
