BD-PP1620

Rac1/CDC42 (Phospho Ser71) Rabbit Polyclonal Antibody

Ras-related C3 botulinum toxin substrate 1 (Cell migration-inducing gene 5 protein;Ras-like protein TC25;p21-Rac1)

常规抗体

RAC1 TC25 MIG5

Rac1/CDC42 (Phospho Ser71)

WB

Human,Mouse,Rat

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

5879

https://www.uniprot.org/uniprot/5879

P63000/P15153/P60763/P60953

https://www.uniprot.org/uniprotkb/P63000/entry

19353

https://www.uniprot.org/uniprot/19353

P63001

https://www.uniprot.org/uniprotkb/P63001

363875

https://www.uniprot.org/uniprot/363875

Q6RUV5

https://www.uniprot.org/uniprotkb/Q6RUV5

Synthesized peptide derived from human Rac1/CDC42 (Phospho Ser71)

This antibody detects endogenous levels of Human,Mouse,Rat Rac1/CDC42 (Phospho Ser71)

WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000

21kD

-20°C/1 year

Polyclonal, Rabbit,IgG

Isoform B is predominantly identified in skin and epithelial tissues from the intestinal tract. Its expression is elevated in colorectal tumors at various stages of neoplastic progression, as compared to their respective adjacent tissues.

Cell membrane ; Lipid-anchor ; Cytoplasmic side . Melanosome . Cytoplasm . Cell projection, lamellipodium . Cell projection, dendrite . Cell junction, synapse . Nucleus . Inner surface of plasma membrane possibly with attachment requiring prenylation of the C-terminal cysteine (PubMed:1903399). Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:17081065). Found in the ruffled border (a late endosomal-like compartment in the plasma membrane) of bone-resorbing osteoclasts. Localizes to the lamellipodium in a SH3RF1-dependent manner (By similarity). In macrophages, cytoplasmic location increases upon CSF1 stimulation (By similarity). Activation by GTP-binding promotes nuclear localization (PubMed:12551911). .

现货

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.