产品名称
EPHB3 (Phospho Tyr608) Rabbit Polyclonal Antibody
别名
Ephrin type-B receptor 3 (EC 2.7.10.1;EPH-like tyrosine kinase 2;EPH-like kinase 2;Embryonic kinase 2;EK2;hEK2;Tyrosine-protein kinase TYRO6)
基因名称
EPHB3 ETK2 HEK2 TYRO6
蛋白名称
EPHB3 (Phospho Tyr608)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/2049
Human Swissprot No.
P54753
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P54753/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/13845
Mouse Swissprot No.
P54754
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/P54754
免疫原
Synthesized peptide derived from human EPHB3 (Phospho Tyr608)
特异性
This antibody detects endogenous levels of Human,Mouse,Rat EPHB3 (Phospho Tyr608)
稀释度
WB 1:1000-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into two groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. This gene encodes a receptor for ephrin-B family members. [provided by RefSeq, Mar 2010],
细胞定位
Cell membrane ; Single-pass type I membrane protein . Cell projection, dendrite .
功能
catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,function:Receptor for members of the ephrin-B family. Binds to ephrin-B1 and -B2.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 SAM (sterile alpha motif) domain.,similarity:Contains 2 fibronectin type-III domains.,tissue specificity:Ubiquitous.,
纯化
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
