产品名称
EPHA1 (Phospho Tyr599) Rabbit Polyclonal Antibody
别名
Ephrin type-A receptor 1 (hEpha1;EC 2.7.10.1;EPH tyrosine kinase;EPH tyrosine kinase 1;Erythropoietin-producing hepatoma receptor;Tyrosine-protein kinase receptor EPH)
基因名称
EPHA1 EPH EPHT EPHT1
蛋白名称
EPHA1 (Phospho Tyr599)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/2041
Human Swissprot No.
P21709
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P21709/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/13835
Mouse Swissprot No.
Q60750
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q60750
免疫原
Synthesized peptide derived from human EPHA1 (Phospho Tyr599)
特异性
This antibody detects endogenous levels of Human EPHA1 (Phospho Tyr599)
稀释度
WB 1:1000-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,function:Receptor for members of the ephrin-A family. Binds with a low affinity to ephrin-A1.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 SAM (sterile alpha motif) domain.,similarity:Contains 2 fibronectin type-III domains.,tissue specificity:Overexpressed in several carcinomas.,
组织表达
Overexpressed in several carcinomas.
细胞定位
Cell membrane ; Single-pass type I membrane protein .
功能
protein amino acid phosphorylation,?phosphorus metabolic process,?phosphate metabolic process,?cell surface receptor linked signal transduction,?enzyme linked receptor protein signaling pathway,?transmembrane receptor protein tyrosine kinase signaling pathway,?phosphorylation,?ephrin receptor signaling pathway,
纯化
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.