产品名称
RBSK Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/64080
Human Swissprot No.
Q9H477
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9H477/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/71336
Mouse Swissprot No.
Q8R1Q9
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8R1Q9
免疫原
Synthesized peptide derived from human RBSK AA range: 168-218
特异性
This antibody detects endogenous levels of RBSK at Human/Mouse
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the carbohydrate kinase PfkB family. The encoded protein phosphorylates ribose to form ribose-5-phosphate in the presence of ATP and magnesium as a first step in ribose metabolism. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013],
细胞定位
Cytoplasm . Nucleus .
功能
catalytic activity:ATP + D-ribose = ADP + D-ribose 5-phosphate.,enzyme regulation:Competitively inhibited by phosphonoacetic acid, etidronate, 2-carboxethylphosphonic acid, N-(phosphonomethyl)glycine, N-(phosphonomethyl)iminodiacetic acid and clodronate.,pathway:Carbohydrate metabolism; D-ribose degradation; D-ribose 5-phosphate from beta-D-ribopyranose: step 2/2.,similarity:Belongs to the carbohydrate kinase pfkB family.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.