产品名称
PDE6G (Phospho Thr22) Rabbit Polyclonal Antibody
别名
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma (GMP-PDE gamma;EC 3.1.4.35)
蛋白名称
PDE6G (Phospho Thr22)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/5148
Human Swissprot No.
P18545
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P18545/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/18588
Mouse Swissprot No.
P09174
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/P09174
免疫原
Synthesized peptide derived from human PDE6G (Phospho Thr22)
特异性
This antibody detects endogenous levels of Human, Mouse PDE6G (Phospho Thr22)
稀释度
WB 1:1000-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes the gamma subunit of cyclic GMP-phosphodiesterase, which is composed of alpha- and beta- catalytic subunits and two identical, inhibitory gamma subunits. This gene is expressed in rod photoreceptors and functions in the phototransduction signaling cascade. It is also expressed in a variety of other tissues, and has been shown to regulate the c-Src protein kinase and G-protein-coupled receptor kinase 2. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2009],
功能
catalytic activity:Guanosine 3',5'-cyclic phosphate + H(2)O = guanosine 5'-phosphate.,function:Participates in processes of transmission and amplification of the visual signal. cGMP-PDEs are the effector molecules in G-protein-mediated phototransduction in vertebrate rods and cones.,online information:Retina International's Scientific Newsletter,similarity:Belongs to the rod/cone cGMP-PDE gamma subunit family.,subunit:Oligomer composed of two catalytic chains (alpha and beta), an inhibitory chain (gamma) and the delta chain.,
纯化
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
