产品名称
BRSK2 (Phospho Thr260) Rabbit Polyclonal Antibody
别名
Serine/threonine-protein kinase BRSK2 (EC 2.7.11.1;Brain-selective kinase 2;EC 2.7.11.26;Brain-specific serine/threonine-protein kinase 2;BR serine/threonine-protein kinase 2;Serine/threonine-protein kinase 29;Serine/threonine-protein kinase SAD-A)
基因名称
BRSK2 C11orf7 PEN11B SADA STK29 HUSSY-12
蛋白名称
BRSK2 (Phospho Thr260)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/9024
Human Swissprot No.
Q8IWQ3
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q8IWQ3/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/75770
Mouse Swissprot No.
Q69Z98
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q69Z98
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/D3ZML2
免疫原
Synthesized peptide derived from human BRSK2 (Phospho Thr260)
特异性
This antibody detects endogenous levels of Human,Mouse,Rat BRSK2 (Phospho Thr260)
稀释度
WB 1:1000-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,enzyme regulation:Activated by phosphorylation on Thr-174 by STK11 in complex with STE20-related adapter-alpha (STRAD alpha) pseudo kinase and CAB39.,function:Required for the polarization of forebrain neurons which endows axons and dendrites with distinct properties, possibly by locally regulating phosphorylation of microtubule-associated proteins.,sequence caution:Translated as Gly.,similarity:Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. AMPK subfamily.,similarity:Contains 1 protein kinase domain.,
组织表达
Detected in pancreas islets (at protein level).
细胞定位
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, perinuclear region. Endoplasmic reticulum. Detected at centrosomes during mitosis. Localizes to the endoplasmic reticulum in response to stress caused by tunicamycin.
功能
catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,enzyme regulation:Activated by phosphorylation on Thr-174 by STK11 in complex with STE20-related adapter-alpha (STRAD alpha) pseudo kinase and CAB39.,function:Required for the polarization of forebrain neurons which endows axons and dendrites with distinct properties, possibly by locally regulating phosphorylation of microtubule-associated proteins.,sequence caution:Translated as Gly.,similarity:Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. AMPK subfamily.,similarity:Contains 1 protein kinase domain.,
纯化
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
