产品名称
PDE6G (Phospho Thr22) Rabbit Polyclonal Antibody
别名
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma (GMP-PDE gamma;EC 3.1.4.35)
蛋白名称
PDE6G (Phospho Thr22)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/5148
Human Swissprot No.
P18545
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P18545/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/18588
Mouse Swissprot No.
P09174
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/P09174
免疫原
Synthesized peptide derived from human PDE6G (Phospho Thr22)
特异性
This antibody detects endogenous levels of Human, Mouse PDE6G (Phospho Thr22)
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes the gamma subunit of cyclic GMP-phosphodiesterase, which is composed of alpha- and beta- catalytic subunits and two identical, inhibitory gamma subunits. This gene is expressed in rod photoreceptors and functions in the phototransduction signaling cascade. It is also expressed in a variety of other tissues, and has been shown to regulate the c-Src protein kinase and G-protein-coupled receptor kinase 2. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2009],
功能
catalytic activity:Guanosine 3',5'-cyclic phosphate + H(2)O = guanosine 5'-phosphate.,function:Participates in processes of transmission and amplification of the visual signal. cGMP-PDEs are the effector molecules in G-protein-mediated phototransduction in vertebrate rods and cones.,online information:Retina International's Scientific Newsletter,similarity:Belongs to the rod/cone cGMP-PDE gamma subunit family.,subunit:Oligomer composed of two catalytic chains (alpha and beta), an inhibitory chain (gamma) and the delta chain.,
纯化
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
